4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
生物活性
Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM.
性状
Solid
IC50 & Target[1][2]
AChE
体外研究(In Vitro)
During a screening program for new agrochemicals from Chinese medicinal herbs, the ethanol extract of Notopterygium incisum rhizomes is found to possess strong nematicidal activity against the two species of nematodes, Bursaphelenchus xylophilus and Meloidogyne incognita. Based on bioactivity-guided fractionation, the four constituents are isolated from the ethanol extract and identified as Columbianetin, Falcarindiol, Falcarinol, and Isoimperatorin. Isoimperatorin also has LC50 values of 21.83 μg/mL against B. xylophilus. When using 15 min UV light treatment, falcarindiol, falcarinol, and isoimperatorin demonstrated almost five times more toxic to the southern root-knot nematodes than in dark treatment while columbianetin showed only two times more toxic. isoimperatorin has been demonstrated to possess insecticidal activity against sever
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
结构分类
Phenylpropanoids
来源
Plants
溶解度数据
体外研究:Ethanol : 8.33 mg/mL(30.82 mM;Need ultrasonic)DMSO : 2.5 mg/mL(9.25 mM;ultrasonic and warming and heat to 60°C)配制储存液