Detailed protocols for TSA-seq are presented, the first sequencing-based method for estimation of cytological proximity of chromosomal loci to spatially discrete nuclear structures, such as nuclear bodies or the nuclear lamina, which is highly reproducible and largely independent of the target protein or antibody choice for labeling a particular nuclear compartment.
Measuring Cytological Proximity of Chromosomal Loci to Defined Nuclear Compartments with TSA-seq.
发布日期：2026/10/29 9:48:43
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