Adenosine.|58-61-7|(腺苷; Adenine riboside; D-Adenosine)-陌孚医药/Medlife

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Adenosine. (Synonyms: 腺苷; Adenine riboside; D-Adenosine)

目录号: PC61667 纯度: ≥99%

CAS No. :58-61-7

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中文名称	Adenosine.
中文别名	阿糖腺苷;9-beta-D-阿拉伯呋喃糖基腺嘌呤;9-Β-D-阿拉伯呋喃糖基腺嘌呤;9-Β-D-阿拉伯呋喃糖腺嘌呤；9-Β-D-ARABINOFURANOSYLADENINE MONOHYDRATE;腺嘌呤阿拉伯糖苷；ADENINE ARABINOSIDE;阿糖腺嘌吟;腺嘌吟阿拉伯糖苷;腺苷;腺嘌呤核苷;（腺苷）腺嘌呤核苷;（腺苷）腺嘌呤核苷,BR;（腺苷）腺嘌呤核苷,对照品;D-腺嘌呤核苷;腺苷对照品;阿糖腺苷；腺嘌呤核苷;阿糖腺苷标准品;四乙酰核糖;腺甘酸 EP标准品;腺苷 USP标准品;腺苷标准品;腺苷(标准品);腺苷；Adenosine;腺苷植物提取物,标准品,对照品；Adenosine,;腺嘌呤核苷(腺苷);9-beta-D-呋喃核糖基腺嘌呤;9-β-D-呋喃核糖基腺嘌呤;腺甙;腺苷；腺尿环核苷；腺嘌呤核苷;腺苷；阿糖腺苷;腺呤配糖;腺尿环核苷;腺嘌呤核苷；腺苷;腺素苷;胰苷;腺嘌呤-9-β-D-呋喃核糖苷;阿糖腺苷,医药级,纯度:>99%;腺昔
英文名称	Adenosine
英文别名	Adenosine;ARABINOSYL-ADENINE;6-AMINO-9-BETA-D-ARABINOFURANOSYLPURINE;ADENINE-BETA-D-ARABINOFURANOSIDE;ADENINE-9-BETA-D-ARABINOFURANOSIDE;9-BETA-D-ARABINOSYLADENINE;9-BETA-D-ARABINOFURANOSYLADENINE;2'-ARAADENOSINE;SPONGOADENOSINE;(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;ADENOSINE(RG);ADENOSINE FREE BASE;9-beta-D-Ribofuranosyladenine;9-β-D-Ribofuranosyladenine;Adenine riboside;Adenine-9-beta-D-ribofuranoside;Adenocor;Adenosin;Adesine;Adrekar;Boniton;D-Adenosine;Myocol;Sandesin;[ "" ];Adenoscan;Adenocard;beta-D-Adenosine;Nucleocardyl;Adenine nucleoside;beta-Adenosine;9-beta-D-Ribofuranosidoadenine;Adenosin [German];9-beta-D-Ribofuranosyl-9H-purin-6-amine;9beta-D-Ribofuranosyladenine;Ade-Rib;6-Amino-9-beta-D-ribofuranosyl-9H-purine;Pallacor;Caswell No. 010B;Adenosine [USAN:BAN];beta-D-Ribofuranoside, adenine-9;6-Amino-9beta-D-ribofuranosyl-9H-purine;(2R,3R,4S,5
Cas No.	58-61-7
分子式	C₁₀H₁₃N₅O₄
分子量	267.24
包装储存	Powder； -20°C； 3 years; 4°C； 2 years；

生物活性

Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

性状

Solid

IC50 & Target[1][2]

Human Endogenous Metabolite
Microbial Metabolite

体外研究(In Vitro)

Adenosine (Adenine riboside) acts on four G-protein coupled receptors: two of them, A1 and A3, are primarily coupled to Gi family G proteins; and two of them, A2A and A2B, are mostly coupled to Gs like G proteins. These receptors are antagonized by xanthines including caffeine. Via these receptors it affects many cells and organs, usually having a cytoprotective function.
Adenosine is an extracellular signaling molecule that is generated from its precursor molecules 5’-adenosine triphosphate (ATP) and 5’-adenosine monophosphate (AMP).
Adenosine is a common metabolite of ATP, which exhibits cytotoxic effects at high concentrations.Adenosine (1.0-4.0 mM; 12-24 hours) inhibits cell viability and triggers ER stress in HepG2 cells.
Adenosine induces apoptosis in a variety of cancer cells. Adenosine (2.0 mM; 12-24 hours) induces autophagy in HepG2 cells. In HepG2 cell li

运输条件

Room temperature or refrigerated transport.

储存方式

Powder； -20°C； 3 years; 4°C； 2 years；

ClinicalTrial

结构分类

Others

溶解度数据	体外研究: DMSO : 33.33 mg/mL(124.72 mM;Need ultrasonic) H₂O : ≥ 6.67 mg/mL(24.96 mM) *≥ means soluble, but saturation unknown.

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Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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