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Valepotriate

(Synonyms: Valtrate)

目录号: PC64485 纯度: ≥99%

Valepotriate 可以从蜘蛛香 (Valeriana jatamansi) 中分离出，具有抗癫痫和抗癌活性。Valepotriate 可以从蜘蛛香 (Valeriana jatamansi) 中分离出，具有抗癫痫和抗癌活性。

CAS No. :18296-44-1

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中文名称	Valepotriate
中文别名	戊曲酯;[(1S,6S,7aS)-4-(乙酰氧甲基)-1-(3-甲基丁酰氧基)螺[6,7a-二氢-1H-环戊并[c]吡喃-7,2'-环氧乙烷]-6-基] 3-甲基丁酸酯;缬草素;缬草三酯;缬草三酯（缬草素、环氧戊喃）;缬草三酯对照品;戊曲酯,缬草三酯;环氧戊喃;VALEPOTRIATE 缬草三酯
英文名称	Valepotriate
英文别名	Valtrate;[(1S,6S,7aS)-4-(Acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-methylbutanoate;Valepotriate;VALTRATE(P)(PLEASE CALL);HalazuchroMe B;tolterodine;ValepotriatuM;ValtratuM;VALTRATE(P);(1S,7R)-4-Acetoxymethyl-6,7aα-dihydrospiro[cyclopenta[c]pyran-7(1H),2'-oxirane]-1α,6α-diol 1,6-bis(3-methylbutanoate);[(7R,7As)-4-(acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-o;Valtrato;Valtrats;L3JQ035X9B;[(1S,6S,7R,7aS)-4-(acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-methylbutanoate;Valtrate [INN];Valtrats [German];Valtratum [INN-Latin];Valtrato [INN-Spanish];MEGxp0_000900;1,7a-Dihydro-1,6-dihydroxyspiro(cyclopenta(c)pyran-7-(6H),2'-oxirane)-4-methanol 4-acetate 1,6-diisova
Cas No.	18296-44-1
分子式	C₂₂H₃₀O₈
分子量	422.47
包装储存	-20°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；

生物活性	Valepotriate can be isolated from Valeriana jatamansi Jones, has anti-epileptic and anti-cancer activities.
性状	Oil
体内研究(In Vivo)	Valepotriate showed significant anti-epileptic activity against MES- and PTZ-induced epilepsy at doses of 5, 10, and 20 mg/kg, and ED50 values for MES- and PTZ-induced epilepsy were 7.84 and 7.19 mg/kg, respectively. Furthermore, valepotriate (10 and 20 mg/kg) can significantly prolong sleeping time and shorten the latency time on the pentobarbital sodium-induced sleeping time test. Furthermore, valepotriate (5, 10, and 20 mg/kg) could significantly up-regulate the expression of GABAA, GAD65, and Bcl-2 and down-regulate the expression of caspase-3, but had no significant effect on the expression of GABAB.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature or refrigerated transport.
储存方式	-20°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；
结构分类	Terpenoids Iridoi
来源	Plants other fami

溶解度数据	体外研究: DMSO : 100 mg/mL(236.70 mM;Need ultrasonic) 配制储存液

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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